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There is 1 airport in Guayaquil. José Joaquín de Olmedo Intl Airport (GYE) is Guayaquil’s primary airport with at least domestic flights and international flights departing from its runways every week. As of today, airlines operate out of José Joaquín de Olmedo Intl Airport (GYE). José Joaquín de Olmedo Intl Airport (GYE) is 2.1 miles from Guayaquil and offers nonstop flights to cities.